abstract：:Cerebral small vessel disease (SVD) is considered the most important vascular contributor to the development of cognitive impairment and dementia. There is increasing awareness that SVD exerts its clinical effects by disrupting white matter connections, predominantly disrupting connections between rich club nodes, a s...

journal_title：NeuroImage. Clinical

authors： van Leijsen EMC,van Uden IWM,Bergkamp MI,van der Holst HM,Norris DG,Claassen JAHR,Kessels RPC,de Leeuw FE,Tuladhar AM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The functional significance of the impairment shown by patients with ADHD on response inhibition tasks is unclear. Dysfunctional behavioral and BOLD responses to rare no-go cues might reflect disruption of response inhibition (mediating withholding the response) or selective attention (identifying the rare c...

journal_title：NeuroImage. Clinical

authors： Hwang S,Meffert H,Parsley I,Tyler PM,Erway AK,Botkin ML,Pope K,Blair RJR

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:The medial temporal lobe atrophy (MTA) and the posterior atrophy (PA) scales allow to assess the degree hippocampal and parietal atrophy from magnetic resonance imaging (MRI) scans. Despite reliable, easy and widespread employment, appropriate normative values are still missing. We aim to provide norms for t...

journal_title：NeuroImage. Clinical

authors： Cotta Ramusino M,Altomare D,Bacchin R,Ingala S,Bnà C,Bonetti M,Costa A,Barkhof F,Nicolosi V,Festari C,Frisoni GB,Boccardi M

更新日期：2019-01-01 00:00:00

abstract：:Age-related degenerative changes in the lumbar spine frequently result in nerve root compression causing severe pain and disability. Given the increasing incidence of lumbar spinal disorders in the aging population and the discrepancies between the use of current diagnostic imaging tools and clinical symptoms, novel m...

journal_title：NeuroImage. Clinical

authors： Hughes SW,Hellyer PJ,Sharp DJ,Newbould RD,Patel MC,Strutton PH

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Multiple pathway models of ADHD suggest that multiple, separable biological pathways may lead to symptoms of the disorder. If this is the case, it should be possible to identify subgroups of children with ADHD based on distinct patterns of brain activity. Previous studies have used latent class analysis (LCA...

journal_title：NeuroImage. Clinical

authors： Lecei A,van Hulst BM,de Zeeuw P,van der Pluijm M,Rijks Y,Durston S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND CONTEXT:Spinal manipulation (SM) is a common treatment for neck and back pain, theorized to mechanically affect the spine leading to therapeutic mechanical changes. The link between specific mechanical effects and clinical improvement is not well supported. SM's therapeutic action may instead be partially me...

journal_title：NeuroImage. Clinical

authors： Weber Ii KA,Wager TD,Mackey S,Elliott JM,Liu WC,Sparks CL

更新日期：2019-01-01 00:00:00

abstract：:Previous studies have demonstrated that migraine is associated with enhanced perception and altered cerebral processing of sensory stimuli. More recently, it has been suggested that this sensory hypersensitivity might reflect a more general enhanced response to aversive emotional stimuli. Using functional magnetic res...

journal_title：NeuroImage. Clinical

authors： Szabó E,Galambos A,Kocsel N,Édes AE,Pap D,Zsombók T,Kozák LR,Bagdy G,Kökönyei G,Juhász G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Vascular mild cognitive impairment (VMCI) is a potentially transitional state between normal aging and vascular dementia. The presence of macroscopic white matter lesions (WML) of moderate or severe extension on brain MRI is the hallmark of the VMCI. OBJECTIVE:To assess the clinical relevance of the frequen...

journal_title：NeuroImage. Clinical

authors： Giorgio A,Di Donato I,De Leucio A,Zhang J,Salvadori E,Poggesi A,Diciotti S,Cosottini M,Ciulli S,Inzitari D,Pantoni L,Mascalchi M,Federico A,Dotti MT,De Stefano N,VMCI-Tuscany Study Group.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Current diagnostic systems for neurodevelopmental disorders do not have clear links to underlying neurobiology, limiting their utility in identifying targeted treatments for individuals. Here, we aimed to investigate differences in functional brain network integrity between traditional diagnostic categories ...

journal_title：NeuroImage. Clinical

authors： Dajani DR,Burrows CA,Odriozola P,Baez A,Nebel MB,Mostofsky SH,Uddin LQ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) may alleviate motor symptoms in Parkinson's disease (PD). However, the neurophysiological effects of tDCS on cortical activation, synchronization, and the relation to clinical motor symptoms and motor integration need characterization. OBJECTIVE:We aimed to exp...

journal_title：NeuroImage. Clinical

authors： Schoellmann A,Scholten M,Wasserka B,Govindan RB,Krüger R,Gharabaghi A,Plewnia C,Weiss D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Grey matter (GM) atrophy in Alzheimer's disease (AD) is most commonly modeled as a function of time. However, this approach does not take into account inter-individual differences in initial disease severity or changes due to aging. Here, we modeled GM atrophy within individuals across the AD clinical spectr...

journal_title：NeuroImage. Clinical

authors： Dicks E,Vermunt L,van der Flier WM,Visser PJ,Barkhof F,Scheltens P,Tijms BM,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To develop a statistical method of combining multimodal MRI (mMRI) of adult glial brain tumours to generate tissue heterogeneity maps that indicate tumour grade and infiltration margins. MATERIALS AND METHODS:We performed a retrospective analysis of mMRI from patients with histological diagnosis of glioma (n =...

journal_title：NeuroImage. Clinical

authors： Raschke F,Barrick TR,Jones TL,Yang G,Ye X,Howe FA

更新日期：2019-01-01 00:00:00

abstract：Background:The aim of this study was to investigate the potential of combined textural feature analysis of contrast-enhanced MRI (CE-MRI) and static O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET for the differentiation between local recurrent brain metastasis and radiation injury since CE-MRI often remains inconclusive. ...

journal_title：NeuroImage. Clinical

authors： Lohmann P,Kocher M,Ceccon G,Bauer EK,Stoffels G,Viswanathan S,Ruge MI,Neumaier B,Shah NJ,Fink GR,Langen KJ,Galldiks N

更新日期：2018-08-19 00:00:00

abstract：Background:Behavioral, cognitive and functional particularities in autism differ according to autism subgroups and might be associated with domain-specific cognitive strengths. It is unknown whether structural changes support this specialization. We investigated the link between cortical folding, its maturation and cog...

journal_title：NeuroImage. Clinical

authors： Duret P,Samson F,Pinsard B,Barbeau EB,Boré A,Soulières I,Mottron L

更新日期：2018-08-04 00:00:00

abstract：:This study hypothesizes that the brain shows hyper connectedness as amyotrophic lateral sclerosis (ALS) progresses. 54 patients (classified as "early stage" or "advanced stage") and 25 controls underwent magnetoencephalography and MRI recordings. The activity of the brain areas was reconstructed, and the synchronizati...

journal_title：NeuroImage. Clinical

authors： Sorrentino P,Rucco R,Jacini F,Trojsi F,Lardone A,Baselice F,Femiano C,Santangelo G,Granata C,Vettoliere A,Monsurrò MR,Tedeschi G,Sorrentino G

更新日期：2018-08-04 00:00:00

abstract：Objective:Generalized tonic-clonic seizures are accompanied by cardiovascular and respiratory sequelae that threaten survival. The frequency of these seizures is a major risk factor for sudden unexpected death in epilepsy (SUDEP), a leading cause of untimely death in epilepsy. The circumstances accompanying such fatal ...

journal_title：NeuroImage. Clinical

authors： Ogren JA,Tripathi R,Macey PM,Kumar R,Stern JM,Eliashiv DS,Allen LA,Diehl B,Engel J Jr,Rani MRS,Lhatoo SD,Harper RM

更新日期：2018-07-18 00:00:00

abstract：Background:Previous publications indicate that Alzheimer's Disease (AD) related cortical atrophy may develop in asymmetric patterns, with accentuation of the left hemisphere. Since fluorodeoxyglucose positron emission tomography (FDG PET) measurements of the regional cerebral metabolic rate of glucose (rCMRgl) provide ...

journal_title：NeuroImage. Clinical

authors： Weise CM,Chen K,Chen Y,Kuang X,Savage CR,Reiman EM,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2018-07-17 00:00:00

abstract：Background:An urgent need exists for faster-acting pharmacological treatments in major depressive disorder (MDD). The glutamatergic modulator ketamine has been shown to have rapid antidepressant effects, but much remains unknown about its mechanism of action. Functional MRI (fMRI) can be used to investigate how ketamin...

journal_title：NeuroImage. Clinical

authors： Reed JL,Nugent AC,Furey ML,Szczepanik JE,Evans JW,Zarate CA Jr

更新日期：2018-07-05 00:00:00

abstract：Background:Most children who are exposed to threat-related adversity (e.g., violence, abuse, neglect) are resilient - that is, they show stable trajectories of healthy psychological development. Despite this, most research on neurodevelopmental changes following adversity has focused on the neural correlates of negativ...

journal_title：NeuroImage. Clinical

authors： Iadipaolo AS,Marusak HA,Paulisin SM,Sala-Hamrick K,Crespo LM,Elrahal F,Peters C,Brown S,Rabinak CA

更新日期：2018-06-27 00:00:00

abstract：:Sporadic cerebral small vessel disease is an important cause of vascular dementia, a syndrome of cognitive impairment together with vascular brain damage. At post-mortem pure vascular dementia is rare, with evidence of co-existing Alzheimer's disease pathology in 95% of cases. This work used MRI to characterize struct...

journal_title：NeuroImage. Clinical

authors： Lambert C,Zeestraten E,Williams O,Benjamin P,Lawrence AJ,Morris RG,Mackinnon AD,Barrick TR,Markus HS

更新日期：2018-06-20 00:00:00

abstract：:SPG11 mutations are the major cause of autosomal recessive Hereditary Spastic Paraplegia. The disease has a wide phenotypic variability indicating many regions of the nervous system besides the corticospinal tract are affected. Despite this, anatomical and phenotypic characterization is restricted. In the present stud...

journal_title：NeuroImage. Clinical

authors： Faber I,Martinez ARM,de Rezende TJR,Martins CR Jr,Martins MP,Lourenço CM,Marques W Jr,Montecchiani C,Orlacchio A,Pedroso JL,Barsottini OGP,Lopes-Cendes Í,França MC Jr

更新日期：2018-06-09 00:00:00

abstract：Introduction:Previous literature has revealed that the anterior temporal lobe (ATL) is the semantic hub of left-sided or mixed semantic dementia (SD), whilst the semantic hub of right-sided SD has not been examined. Methods:Seventeen patients with right-sided SD, 18 patients with left-sided SD and 20 normal controls (...

journal_title：NeuroImage. Clinical

authors： Chen K,Ding J,Lin B,Huang L,Tang L,Bi Y,Han Z,Lv Y,Guo Q

更新日期：2018-05-29 00:00:00

abstract：:When differential diagnosis of dementia includes both Alzheimer's disease (AD) and the behavioural variant of frontotemporal dementia (bvFTD), distribution of cerebral glucose metabolism as measured using [18F]‑2‑fluoro‑2‑deoxy‑d‑glucose positron emission tomography ([18F]FDG-PET) may be helpful. One important clue fo...

journal_title：NeuroImage. Clinical

authors： Scheltens NME,van der Weijden K,Adriaanse SM,van Assema D,Oomen PP,Krudop WA,Lammertsma AA,Barkhof F,Koene T,Teunissen CE,Scheltens P,van der Flier WM,Pijnenburg YAL,Yaqub M,Ossenkoppele R,van Berckel BNM

更新日期：2018-05-22 00:00:00

abstract：Background:Although brain atrophy is considered to be a downstream marker of Alzheimer's disease (AD), subtle changes may allow to identify healthy subjects at risk of developing AD. As the ability to select at-risk persons is considered to be important to assess the efficacy of drugs and as MRI is a widely available i...

journal_title：NeuroImage. Clinical

authors： Van Schependom J,Niemantsverdriet E,Smeets D,Engelborghs S

更新日期：2018-05-19 00:00:00

abstract：:While gray matter (GM) anomalies have been reported for attention-deficit/hyperactivity disorder (ADHD), investigating their associations with cognitive deficits and individual symptom domains can help pinpoint the neural underpinnings critical for the pathology of ADHD, particularly the persist form of ADHD. In this ...

journal_title：NeuroImage. Clinical

authors： Duan K,Chen J,Calhoun VD,Lin D,Jiang W,Franke B,Buitelaar JK,Hoogman M,Arias-Vasquez A,Turner JA,Liu J

更新日期：2018-05-02 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is a trauma- and stressor-related disorder that may emerge following a traumatic event. Neuroimaging studies have shown evidence of functional abnormality in many brain regions and systems affected by PTSD. Exaggerated threat detection associated with abnormalities in the salience ...

journal_title：NeuroImage. Clinical

authors： Yuan H,Phillips R,Wong CK,Zotev V,Misaki M,Wurfel B,Krueger F,Feldner M,Bodurka J

更新日期：2018-04-21 00:00:00

abstract：Background:Behavioral inhibition (BI) is an early-appearing temperament trait and a robust predictor of social anxiety disorder (SAD). Both BI and anxiety may have distinct patterns of emotion processing marked by heightened neural responses to threat cues. BI and anxious children display similar frontolimbic patterns ...

journal_title：NeuroImage. Clinical

authors： Auday ES,Taber-Thomas BC,Pérez-Edgar KE

更新日期：2018-04-12 00:00:00

abstract：:In this retrospective cross-sectional study we compared 123I‑N‑ω‑fluoropropyl‑2β‑carbomethoxy‑3β‑(4‑iodophenyl)nortropane (123I-FP-CIT) binding to the striatal dopamine and the extrastriatal serotonin transporter (DAT and SERT, respectively) between Parkinson's disease (PD) and dementia with Lewy bodies (DLB) to gain ...

journal_title：NeuroImage. Clinical

authors： Joling M,Vriend C,van der Zande JJ,Lemstra AW,van den Heuvel OA,Booij J,Berendse HW

更新日期：2018-04-06 00:00:00

abstract：:Selective or 'picky' eating habits are common among those with autism spectrum disorder (ASD). These behaviors are often related to aberrant sensory experience in individuals with ASD, including heightened reactivity to food taste and texture. However, very little is known about the neural mechanisms that underlie tas...

journal_title：NeuroImage. Clinical

authors： Avery JA,Ingeholm JE,Wohltjen S,Collins M,Riddell CD,Gotts SJ,Kenworthy L,Wallace GL,Simmons WK,Martin A

更新日期：2018-04-04 00:00:00

abstract：:Neuropsychological assessment, brain imaging and computational modelling have augmented our understanding of the multifaceted functional deficits in people with language disorders after stroke. Despite the volume of research using each technique, no studies have attempted to assimilate all three approaches in order to...

journal_title：NeuroImage. Clinical

authors： Tochadse M,Halai AD,Lambon Ralph MA,Abel S

更新日期：2018-03-27 00:00:00

abstract：:Biomarkers in whichever modality are tremendously important in diagnosing of disease, tracking disease progression and clinical trials. This applies in particular for disorders with a long disease course including pre-symptomatic stages, in which only subtle signs of clinical progression can be observed. Magnetic reso...

journal_title：NeuroImage. Clinical

authors： Hohenfeld C,Werner CJ,Reetz K

更新日期：2018-03-16 00:00:00

abstract：Background:There is an ongoing debate whether primary lateral sclerosis (PLS) should be regarded as an independent disease entity separate from amyotrophic lateral sclerosis (ALS) or as a slowly progressive variant of ALS. Objective:The study was designed to investigate specific white matter alterations in diffusion t...

journal_title：NeuroImage. Clinical

authors： Müller HP,Gorges M,Kassubek R,Dorst J,Ludolph AC,Kassubek J

更新日期：2018-03-15 00:00:00

abstract：:Apraxia of speech is a motor speech disorder thought to result from impaired planning or programming of articulatory movements. It can be the initial or only manifestation of a degenerative disease, termed primary progressive apraxia of speech (PPAOS). The aim of this study was to use task-free functional magnetic res...

journal_title：NeuroImage. Clinical

authors： Botha H,Utianski RL,Whitwell JL,Duffy JR,Clark HM,Strand EA,Machulda MM,Tosakulwong N,Knopman DS,Petersen RC,Jack CR Jr,Josephs KA,Jones DT

更新日期：2018-03-03 00:00:00

abstract：:Abnormal brain resting-state functional connectivity has been consistently observed in patients affected by schizophrenia (SCZ) using functional MRI and other neuroimaging techniques. Graph theoretical methods provide a framework to investigate these defective functional interactions and their effects on the organizat...

journal_title：NeuroImage. Clinical

authors： Bordier C,Nicolini C,Forcellini G,Bifone A

更新日期：2018-03-01 00:00:00

abstract：:The ability to empathise relies in part on using one's own affective experience to simulate the affective experience of others. This process is supported by a number of brain areas including the anterior insula (AI), anterior cingulate cortex (ACC), medial prefrontal cortex (mPFC), and the amygdala. Children with cond...

journal_title：NeuroImage. Clinical

authors： Sethi A,O'Nions E,McCrory E,Bird G,Viding E

更新日期：2018-02-28 00:00:00

abstract：:Attention Deficit Hyperactivity Disorder (ADHD) is a disorder affecting cognitive control. These functions are important to achieve goals when different actions need to be executed in close succession. This type of multi-component behavior, which often further requires the processing of information from different moda...

journal_title：NeuroImage. Clinical

authors： Bluschke A,Gohil K,Petzold M,Roessner V,Beste C

更新日期：2018-02-27 00:00:00

abstract：:Multiple genes have been implicated in Parkinson disease pathogenesis, but the relationship between regional expression of these genes and regional dysfunction across the brain is unknown. We address this question by joint analysis of high resolution magnetic resonance imaging data from the Parkinson's Progression Mar...

journal_title：NeuroImage. Clinical

authors： Freeze B,Acosta D,Pandya S,Zhao Y,Raj A

更新日期：2018-01-31 00:00:00

abstract：:The ventral intermediate nucleus (VIM) of the thalamus is an established surgical target for stereotactic ablation and deep brain stimulation (DBS) in the treatment of tremor in Parkinson's disease (PD) and essential tremor (ET). It is centrally placed on a cerebello-thalamo-cortical network connecting the primary mot...

journal_title：NeuroImage. Clinical

authors： Akram H,Dayal V,Mahlknecht P,Georgiev D,Hyam J,Foltynie T,Limousin P,De Vita E,Jahanshahi M,Ashburner J,Behrens T,Hariz M,Zrinzo L

更新日期：2018-01-28 00:00:00

abstract：:Patients with schizophrenia show response inhibition deficits equal to or greater than those seen in impulse-control disorders, and these deficits contribute to poor outcome. However, little is known about the circuit abnormalities underlying this impairment. To address this, we examined stop signal task performance i...

journal_title：NeuroImage. Clinical

authors： Hoptman MJ,Parker EM,Nair-Collins S,Dias EC,Ross ME,DiCostanzo JN,Sehatpour P,Javitt DC

更新日期：2018-01-06 00:00:00

abstract：:The various models proposed for the mediation of auditory verbal hallucinations (AVH) implicate a considerable number of brain areas and mechanisms. To establish which of those mechanisms are actually involved in the mediation of AVH, we developed a novel method to analyze functional MRI data, which allows for the det...

journal_title：NeuroImage. Clinical

authors： Looijestijn J,Blom JD,Hoek HW,Renken R,Liemburg E,Sommer IEC,Aleman A,Goekoop R

更新日期：2018-01-01 00:00:00